Karacostas D, Artemis N, Giannopoulos S, Milonas I, Bogousslavsky J
B Dept. of Neurology, Aristotelian University of Thessaloniki, Greece.
Funct Neurol. 1994 Sep-Oct;9(5):265-8.
A 28-year-old, previously healthy, normotensive woman suddenly developed an acute pseudobulbar palsy with dysarthria, dysphagia, hypernasal voice and mild right arm paresis. Extensive laboratory investigations excluded all other possible causes of acute pseudobulbar palsy (neoplastic, inflammatory, demyelinative, myasthenic) and an MRI study demonstrated bilateral isolated thalamic infarcts. Oral contraceptives and smoking were the only possible stroke risk factors found and cerebral diaschisis the most tenuous explanation proposed. To our knowledge, this is the first report indicating that bilateral thalamic infarction on specific nuclei could be manifested as acute pseudobulbar palsy.
一名28岁、既往健康、血压正常的女性突然出现急性假性延髓麻痹，伴有构音障碍、吞咽困难、鼻音过重及右臂轻度无力。广泛的实验室检查排除了急性假性延髓麻痹的所有其他可能病因（肿瘤性、炎症性、脱髓鞘性、重症肌无力性），磁共振成像（MRI）研究显示双侧孤立性丘脑梗死。口服避孕药和吸烟是仅发现的可能的卒中危险因素，而大脑交叉性失联络是提出的最牵强的解释。据我们所知，这是首例表明特定核团的双侧丘脑梗死可表现为急性假性延髓麻痹的报告。
