Gené M, Huguet E, Sánchez-García C, Moreno P, Corbella J, Mezquita J
Department of Legal Medicine, Faculty of Medicine, University of Barcelona, Spain.
Hum Hered. 1995 Mar-Apr;45(2):70-4. doi: 10.1159/000154262.
Allele and genotype frequencies for the 3'-ApoB locus were determined in a population sample from Catalonia (northeast Spain) using PCR amplification and nonradioactive detection. In a total of 308 unrelated individuals, 16 alleles and 50 genotypes were observed. The 3'-ApoB locus demonstrated a heterozygosity of 80%. The distribution of genotypes is in agreement with expected values according to the Hardy-Weinberg equilibrium.
采用聚合酶链反应（PCR）扩增及非放射性检测方法，对来自加泰罗尼亚（西班牙东北部）的人群样本测定了3'-载脂蛋白B（ApoB）位点的等位基因和基因型频率。在总共308名无亲缘关系的个体中，观察到16个等位基因和50种基因型。3'-ApoB位点的杂合度为80%。基因型的分布符合哈迪-温伯格平衡的预期值。
