Betti R, Inselvini E, Carducci M, Crosti C
Dermatology Clinic IV, Hospital S. Paolo, Milan, Italy.
Int J Dermatol. 1995 Mar;34(3):174-6. doi: 10.1111/j.1365-4362.1995.tb01561.x.
Basal cell carcinomas (BCC) are the most frequently diagnosed skin cancers. The relationships between some clinical parameters, such as sex, age, and location of the tumor, and the histologic patterns play an important role as factors predictive of recurrence and treatment implications.
A total of 693 patients with BCC, divided according to sex, age, and location of the tumor were studied. The histologic patterns considered were nodular, superficial, and morpheiform BCC and fibroepithelioma. The correlation between clinical and histologic parameters was analyzed.
All histologic patterns considered were most commonly represented in the 7th and 8th decades. There were no sex differences. A prevalence of a superficial pattern for sun-unexposed areas and of a nodular pattern for sun-exposed areas was observed. The morpheiform pattern showed no correlation with any body site. The fibroepithelioma showed an absolute prevalence for the lumbosacral region.
Age does not seem to be a discriminant or permissive factor for a particular histologic pattern of BCC. The prevalence of some subtypes for a particular body area may be explained on the basis of local predisposing conditions affecting the histologic development of the tumor.
基底细胞癌（BCC）是最常被诊断出的皮肤癌。一些临床参数，如性别、年龄和肿瘤位置，与组织学模式之间的关系，作为预测复发和治疗意义的因素发挥着重要作用。
对总共693例基底细胞癌患者进行了研究，这些患者根据性别、年龄和肿瘤位置进行了分组。所考虑的组织学模式为结节状、浅表性和浸润性基底细胞癌以及纤维上皮瘤。分析了临床和组织学参数之间的相关性。
所考虑的所有组织学模式在70岁和80岁年龄段最为常见。不存在性别差异。观察到非暴露于阳光部位以浅表模式为主，而暴露于阳光部位以结节模式为主。浸润性模式与任何身体部位均无相关性。纤维上皮瘤在腰骶部区域有绝对的患病率。
年龄似乎不是基底细胞癌特定组织学模式的判别或允许因素。特定身体部位某些亚型的患病率可以根据影响肿瘤组织学发展的局部易感条件来解释。
