再探平卡斯纤维上皮瘤
Fibroepithelioma of Pinkus Revisited.
作者信息
Haddock Ellen S, Cohen Philip R
机构信息
School of Medicine, University of California San Diego, San Diego, CA, USA.
Department of Dermatology, University of California San Diego, San Diego, CA, USA.
出版信息
Dermatol Ther (Heidelb). 2016 Sep;6(3):347-62. doi: 10.1007/s13555-016-0123-8. Epub 2016 Jun 21.
BACKGROUND
Fibroepithelioma of Pinkus (FeP) is considered a variant of basal cell carcinoma (BCC); however, in the past 20 years, some researchers have argued for its classification as a trichoblastoma. Recently, use of a new immunostaining marker and further dermoscopic characterization of FeP have advanced the debate about its proper classification.
PURPOSE
A review of the evidence for and against classification of FeP as BCC or trichoblastoma is presented.
METHODS
Using PubMed, the term FeP was searched and relevant citations were assessed. Additional relevant articles were identified from references of key papers.
RESULTS
FeP shares characteristics of both trichoblastoma and BCC.
CONCLUSION
Derived from the same cell type, BCC and trichoblastoma may be best considered as representing opposite ends of a spectrum of differentiation, with FeP deserving an intermediate classification.
背景
平卡斯纤维上皮瘤（FeP）被认为是基底细胞癌（BCC）的一种变体；然而，在过去20年里，一些研究人员主张将其归类为毛母细胞瘤。最近，一种新的免疫染色标志物的使用以及FeP的进一步皮肤镜特征描述推动了关于其正确分类的争论。
目的
对支持和反对将FeP分类为BCC或毛母细胞瘤的证据进行综述。
方法
使用PubMed搜索FeP一词并评估相关引文。从关键论文的参考文献中识别出其他相关文章。
结果
FeP兼具毛母细胞瘤和BCC的特征。
结论
BCC和毛母细胞瘤源自同一细胞类型，或许最好将它们视为代表了分化谱系的两端，而FeP值得进行中间分类。
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