Hudson-Peacock M J, Matthews J N, Lawrence C M
Department of Dermatology, Royal Victoria Infirmary, Newcastle-upon-Tyne, United Kingdom.
J Am Acad Dermatol. 1995 Jun;32(6):1010-5. doi: 10.1016/0190-9622(95)91341-6.
Skin wounds differ in shape and size compared with the planned excision, and skin shrinks after excision and fixation.
This study was designed to quantify and to analyze the differences between the size and shape of the planned excision, wound, and specimen.
Eighty-six patients with 93 benign or malignant skin tumors were prospectively studied. Length and width measurements were made of the lesion, planned surgical excision, postexcision wound, and prefixation and postfixation specimens. The results were analyzed to identify the effects of patient age and sex, and lesion type and site.
Wound size was larger than planned excision size in 90% of wounds, and this effect was greatest in young patients and at trunk and limb sites. Excision and fixation caused the specimens to shrink so that the postfixation area was on average 48% of the planned excision area; benign tumors shrank more than malignant tumors.
Significant differences among planned excision, wound, and specimen sizes are influenced by patient age and by lesion site and type. These results demonstrate that wound size is not equivalent to tumor size, a conclusion often made in Mohs surgery. Furthermore, assessment of tumor clearance margins from fixed tissue does not reflect in vivo clearance margins.
与计划切除相比,皮肤伤口在形状和大小上存在差异,且切除并固定后皮肤会收缩。
本研究旨在量化并分析计划切除、伤口及标本在大小和形状上的差异。
前瞻性研究了86例患有93个良性或恶性皮肤肿瘤的患者。对病变、计划手术切除、切除后伤口以及固定前和固定后标本进行长度和宽度测量。分析结果以确定患者年龄和性别、病变类型和部位的影响。
90%的伤口大小大于计划切除大小,这种影响在年轻患者以及躯干和四肢部位最为明显。切除并固定导致标本收缩,使得固定后面积平均为计划切除面积的48%;良性肿瘤比恶性肿瘤收缩得更多。
计划切除、伤口和标本大小之间的显著差异受患者年龄、病变部位和类型影响。这些结果表明伤口大小并不等同于肿瘤大小,这是莫氏手术中常得出的结论。此外,对固定组织的肿瘤切缘评估并不能反映体内切缘情况。