Cooper C
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, UK.
J Rheumatol Suppl. 1995 Feb;43:10-2.
Osteoarthritis (OA) is now recognized as a major public health problem. The risk of OA depends upon factors that increase generalized susceptibility to the disorder, as well as biomechanical factors that modify risk at specific joint sites. Occupational physical activity is one of the important influences in this latter category. Epidemiological evidence has begun to mount that occupational physical activity is a determinant of the risk of knee and hip OA. Occupations that involve regular knee bending and heavy lifting confer a greater likelihood of developing knee OA, while there appears to be a particular propensity for hip OA among farmers. Further research into these relationships will have two important consequences: (1) The issue whether industrial recompense is justified for workers in these industries who develop OA will be clarified. (2) A clearer understanding of the pathophysiology of these relationships will lead to more effective preventive strategies.
骨关节炎（OA）如今被视为一个重大的公共卫生问题。OA的风险取决于增加对该疾病普遍易感性的因素，以及改变特定关节部位风险的生物力学因素。职业体力活动是后一类中的重要影响因素之一。流行病学证据已开始增多，表明职业体力活动是膝关节和髋关节OA风险的一个决定因素。涉及经常屈膝和重物搬运的职业，患膝关节OA的可能性更大，而农民似乎特别容易患髋关节OA。对这些关系的进一步研究将产生两个重要结果：（1）将澄清对于这些行业中患OA的工人，产业补偿是否合理的问题。（2）对这些关系病理生理学的更清晰理解将带来更有效的预防策略。
