Optenberg S A, Wojcik B E, Thompson I M
Center for Healthcare Education and Studies, Army Medical Center and School, San Antonio, Texas, USA.
J Urol. 1995 Jun;153(6):1870-2. doi: 10.1016/s0022-5347(01)67334-8.
Recent evidence from an analysis of Medicare patients undergoing radical prostatectomy has suggested that perioperative mortality may be substantially greater than that reported in institutional series. To estimate the perioperative mortality and survival of patients of a younger and potentially more representative population of the United States, Civilian Health and Medical Program of the Uniformed Services institutional claims data from October 1, 1987 to January 1, 1993 were analyzed. A total of 1,059 subjects was examined of an average of 60.0 years and all were younger than 65 years. Using Kaplan-Meier estimates, mortality rates following surgery were calculated to be 0.28% at 30 days, 0.28% at 90 days, 1.02% at 1 year, 1.95% at 2 years, 3.14% at 3 years and 4.64% at 4 years. Observed 1 to 5 mortality rates in this series ranged from 0.362 to 0.487 of the expected mortality when compared to the general population and they were statistically significant. At 30 and 90 days postoperatively 3.1% and 4.6% of the patients were rehospitalized. Data demonstrated that mortality and morbidity from radical prostatectomy were low and that conclusions drawn on outcomes of treatment for carcinoma of the prostate should focus on the entire age range of patients who undergo this procedure in the United States.
对接受根治性前列腺切除术的医疗保险患者进行分析的最新证据表明,围手术期死亡率可能远高于机构系列报道的死亡率。为了估计美国较年轻且可能更具代表性人群的围手术期死亡率和生存率,对1987年10月1日至1993年1月1日期间美国军队医疗计划机构的索赔数据进行了分析。共检查了1059名平均年龄为60.0岁且均未满65岁的受试者。采用Kaplan-Meier估计法,计算出术后30天死亡率为0.28%,90天为0.28%,1年为1.02%,2年为1.95%,3年为3.14%,4年为4.64%。与普通人群相比,该系列中观察到的1至5年死亡率为预期死亡率的0.362至0.487,且具有统计学意义。术后30天和90天,分别有3.1%和4.6%的患者再次住院。数据表明,根治性前列腺切除术的死亡率和发病率较低,关于前列腺癌治疗结果的结论应关注美国接受该手术的所有年龄段患者。