Figueroa T E, Benaim E, Griggs S T, Hvizdala E V
Department of Surgery, University of South Florida Health Science Center, Tampa, USA.
J Urol. 1995 Jun;153(6):1987-9.
The prevalence of enuresis and management options for this condition were studied in our population of sickle cell patients. A total of 91 active patients (6 to 21 years old) followed at our regional sickle cell center was surveyed for the symptoms of primary nocturnal enuresis. Of the 91 patients 27 (29.6%) had primary nocturnal enuresis. Of those with enuresis 17 had homozygous sickle cell anemia, 5 had hemoglobin sickle cell disease, 4 had sickle cell beta + thalassemia and 1 had sickle cell beta zero-thalassemia. Of 10 patients who elected to receive intranasal desmopressin acetate 6 (60%) had complete or partial resolution of nocturnal enuresis. Our data confirm the high prevalence of nocturnal enuresis in patients with sickle cell disease and support the role of desmopressin acetate in the treatment of these patients.
我们对镰状细胞病患者群体中的遗尿症患病率及该病的管理方案进行了研究。我们对在我们地区镰状细胞中心随访的91名活跃患者（6至21岁）进行了原发性夜间遗尿症状的调查。在这91名患者中，27名（29.6%）患有原发性夜间遗尿症。在患有遗尿症的患者中，17名患有纯合子镰状细胞贫血，5名患有血红蛋白镰状细胞病，4名患有镰状细胞β+地中海贫血，1名患有镰状细胞β0地中海贫血。在选择接受醋酸去氨加压素鼻内给药的10名患者中，6名（60%）的夜间遗尿症得到了完全或部分缓解。我们的数据证实了镰状细胞病患者中夜间遗尿症的高患病率，并支持醋酸去氨加压素在治疗这些患者中的作用。
