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[帕金森病立体定向丘脑切开术后对认知功能和日常生活活动的影响]

[Effects on cognitive function and activities of daily living after stereotactic thalamotomy for Parkinson's disease].

作者信息

Maeshima S, Nakai K, Nakai E, Uematsu Y, Ozaki F, Terada T, Nakakita K, Itakura T, Komai N

机构信息

Department of Neurological Surgery, Wakayama Medical College, Japan.

出版信息

No Shinkei Geka. 1995 May;23(5):417-21.

PMID:7753321
Abstract

Stereotactic thalamotomy was performed in ten patients with Parkinson's disease for the suppression of their tremor. After VL-thalamotomy, contralateral tremor and rigidity disappeared or was significantly reduced. Activities of daily living (ADL) measured by functional independence measure and Parkinson's disability score were improved postoperatively in all patients. There was significant improvement in anxiety index. However, other neuropsychological tests showed no significant change postoperatively. ADL improved after thalamotomy. It is concluded that stereotactic VL-thalamotomy is a useful treatment which improves ADL without cognitive dysfunction.

摘要

对10例帕金森病患者进行了立体定向丘脑切开术以抑制震颤。在进行腹外侧丘脑切开术后,对侧震颤和强直消失或显著减轻。所有患者术后通过功能独立性测量和帕金森病残疾评分评估的日常生活活动(ADL)均得到改善。焦虑指数有显著改善。然而,其他神经心理学测试显示术后无显著变化。丘脑切开术后ADL得到改善。结论是立体定向腹外侧丘脑切开术是一种有用的治疗方法,可改善ADL且无认知功能障碍。

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