Meléndez-Manzano J A, González-Ortíz J, Meléndez-Manzano E, Lavalle-Martínez J, Schiaffini-Ruiz M C, Vélez-Quintana Roo J O
Facultad de Medicina de la Benemérita Universidad Autónoma de Puebla, México.
Rev Invest Clin. 1996 Nov-Dec;48(6):449-52.
To determine the therapeutic efficiency of the stereotactic thalamotomy in patients with Parkinson's disease not responsive to medical treatment.
We performed four stereotactic thalamotomies using Leksell's system for the inactivation of the thalamic ventrolateralis nucleus.
Upon re-examination 5 to 58 months after surgery, complete relief of tremor, rigidity and pain was observed; only one case showed a light tremor in the contralateral side three months after surgery.
Stereotactic thalamotomy is of benefit for the control of medically refractory parkinsonism.
确定立体定向丘脑切开术对药物治疗无效的帕金森病患者的治疗效果。
我们使用Leksell系统进行了4例立体定向丘脑切开术，以灭活丘脑腹外侧核。
术后5至58个月复查时，观察到震颤、强直和疼痛完全缓解；仅1例在术后3个月对侧出现轻度震颤。
立体定向丘脑切开术有助于控制药物难治性帕金森病。
