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老年乳腺癌患者的临床流行病学研究结果

[Clinico-epidemiological findings in breast carcinoma in elderly patients].

作者信息

Caruso U, Bianco V, Chiodini S, Riondino G, Veronesi S, Giunta S

机构信息

Dipartimento di Chirurgia, Università degli Studi di Roma Tor Vergata.

出版信息

Minerva Med. 1995 Jan-Feb;86(1-2):33-6.

PMID:7753435
Abstract

Old age certainly represents one of the major risk factors for the development of neoplasia. In breast cancer the incidence rises with age and continues until the age of 84. In EEC countries approximately 140,000 new cases are reported every year and at the end of the 80s there were 10,983 deaths from breast cancer in Italy, an increase of over per 1000 women each year. Fifty par cent of new cases were diagnosed in women aged over 65. The efficiency of a screening programme is evaluated by the fall in mortality rates in the population included in the programme compared to that not included. Results from controlled studies have confirmed the efficacy of breast cancer screening in women aged between 50-70, showing a significant drop in mortality rates which range between 21 and 36%. Adequate diagnostic and therapeutic management are of primary importance and screening programmes are organised in highly efficient structures using specifically trained staff. This underlines the need to set up appropriate services and structures for the prevention and treatment of breast cancer in elderly women, given that the latter represent the most frequently affected age group. Old age should be considered a natural extension of life and all elderly women have the right to receive treatment to prevent breast cancer.

摘要

老年无疑是肿瘤发生的主要危险因素之一。在乳腺癌中,发病率随年龄增长而上升,一直持续到84岁。在欧洲经济共同体国家,每年约报告140,000例新病例,80年代末意大利有10,983人死于乳腺癌,每年每1000名女性中的死亡人数有所增加。50%的新病例是在65岁以上的女性中诊断出来的。筛查项目的效率是通过与未纳入项目的人群相比,项目所涵盖人群的死亡率下降来评估的。对照研究结果证实了50至70岁女性乳腺癌筛查的有效性,死亡率显著下降,降幅在21%至36%之间。充分的诊断和治疗管理至关重要,筛查项目在配备经过专门培训人员的高效机构中组织开展。鉴于老年女性是受影响最频繁的年龄组,这凸显了为老年女性建立预防和治疗乳腺癌的适当服务和机构的必要性。老年应被视为生命的自然延续,所有老年女性都有权接受预防乳腺癌的治疗。

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