Blumberg A, Zehnder C, Burckhardt J J
Department of Medicine, Kantonsspital Aarau, Switzerland.
Nephrol Dial Transplant. 1995;10(2):230-3.
A prospective study was begun in our haemodialysis unit after four previously negative patients were found to be anti-HCV positive. A dedicated area and dedicated dialysis equipment (but not a separate room) were assigned to anti-HCV-positive patients and testing for HCV antibodies was performed every 3 months. A total of 131 patients were treated during the study period of 18 months. Of these, 50 patients were dialysed during the entire 18 months, and 21 were available to be tested six or more months after having left the centre. During the first 6 weeks after implementing the precautions two more anti-HCV-positive patients were detected. However, during the rest of the study period no further newly infected patients were found. It is concluded that the spread of HCV infection in a haemodialysis environment can be prevented by limited isolation procedures.
在我们的血液透析科室，自发现4例之前丙肝抗体检测呈阴性的患者转为抗丙肝病毒（anti-HCV）阳性后，开展了一项前瞻性研究。为抗丙肝病毒阳性患者分配了专用区域和专用透析设备（但不是单独的房间），并每3个月进行一次丙肝抗体检测。在为期18个月的研究期间，共治疗了131例患者。其中，50例患者在整个18个月期间接受透析，21例患者在离开中心6个月或更长时间后仍可接受检测。在实施预防措施后的前6周内，又检测到2例抗丙肝病毒阳性患者。然而，在研究的其余时间里，未发现新的感染患者。得出的结论是，通过有限的隔离程序可以预防血液透析环境中丙肝病毒感染的传播。
