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功能磁共振成像揭示人类多个视觉区域的边界

Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging.

作者信息

Sereno M I, Dale A M, Reppas J B, Kwong K K, Belliveau J W, Brady T J, Rosen B R, Tootell R B

机构信息

University of California, San Diego, La Jolla 92093-0515, USA.

出版信息

Science. 1995 May 12;268(5212):889-93. doi: 10.1126/science.7754376.

DOI:10.1126/science.7754376
PMID:7754376
Abstract

The borders of human visual areas V1, V2, VP, V3, and V4 were precisely and noninvasively determined. Functional magnetic resonance images were recorded during phase-encoded retinal stimulation. This volume data set was then sampled with a cortical surface reconstruction, making it possible to calculate the local visual field sign (mirror image versus non-mirror image representation). This method automatically and objectively outlines area borders because adjacent areas often have the opposite field sign. Cortical magnification factor curves for striate and extrastriate cortical areas were determined, which showed that human visual areas have a greater emphasis on the center-of-gaze than their counterparts in monkeys. Retinotopically organized visual areas in humans extend anteriorly to overlap several areas previously shown to be activated by written words.

摘要

人类视觉区域V1、V2、VP、V3和V4的边界被精确且无创地确定。在相位编码视网膜刺激期间记录功能磁共振图像。然后用皮质表面重建对该体数据集进行采样,从而能够计算局部视野标志(镜像与非镜像表示)。由于相邻区域通常具有相反的视野标志,该方法能自动且客观地勾勒出区域边界。确定了纹状和纹外皮质区域的皮质放大因子曲线,结果表明人类视觉区域比猴子的对应区域更强调注视中心。人类视网膜拓扑组织的视觉区域向前延伸,与先前显示由书面文字激活的几个区域重叠。

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