Itin P H, Rufli T
Dermatologische Klinik, Universitätsspital Basel.
Ther Umsch. 1995 Apr;52(4):236-42.
Diseases of the skin and the gastrointestinal tract may occur together. It is important to examine the skin of everyone showing a gastrointestinal problem. Gastrointestinal signs and symptoms in dermatologic diseases may occur with dysphagia, abdominal pain, gastrointestinal bleeding and diarrhea with or without malabsorption. In general the cause is found in a genetic disorder, or it is infectious, drug-induced, inflammatory or related to a malignant disorder. Polyposis are hamartomatous tumors or result as an inflammatory reaction. All these syndromes may present with cutaneous lesions. As malignant degeneration of polyps often develops, the early diagnosis and preventive treatment is crucial. Inflammatory bowel disease is often associated with skin complications such as pyoderma gangrenosum and erythema nodosum. Malignant disorders in the gut may metastasize into the skin or may produce rather typical paraneoplastic changes.
皮肤疾病和胃肠道疾病可能同时发生。对每一位有胃肠道问题的患者进行皮肤检查很重要。皮肤病中的胃肠道体征和症状可能伴有吞咽困难、腹痛、胃肠道出血以及腹泻，可伴有或不伴有吸收不良。一般来说，病因是遗传性疾病、感染、药物引起、炎症或与恶性疾病有关。息肉病是错构瘤性肿瘤或由炎症反应导致。所有这些综合征都可能出现皮肤病变。由于息肉常常发生恶性变，早期诊断和预防性治疗至关重要。炎症性肠病常伴有皮肤并发症，如坏疽性脓皮病和结节性红斑。肠道恶性疾病可能转移至皮肤，或产生相当典型的副肿瘤性改变。
