[使用荧光探针研究辐射对红细胞膜结构的影响]
[Effect of radiation on erythrocyte membrane structure using fluorescent probes].
作者信息
Gorbenko G P, Krupin V D, Tovstiak V V
出版信息
Ukr Biokhim Zh (1978). 1994 May-Jun;66(3):71-5.
PMID:7754561
Abstract
The effect of electrons with the energy of 5 MeV on the erythrocyte membrane structure was investigated using a fluorescent probe (4-dimethylaminostiryl)-1-methylpyridinium (DSM). Analysis of a competitive binding of DSM and ribonuclease with the erythrocyte ghosts has shown that irradiation causes an increase in the constant of protein association with membranes. It is suggested that a negative surface change increase with irradiation.
摘要
利用荧光探针（4-二甲基氨基苯乙烯基）-1-甲基吡啶鎓（DSM）研究了能量为5兆电子伏的电子对红细胞膜结构的影响。对DSM和核糖核酸酶与红细胞血影的竞争性结合分析表明，辐照会导致蛋白质与膜结合常数增加。据推测，辐照会使表面负电荷增加。
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