[使用荧光探针研究辐射诱导的膜结构变化]
[Study of radiation-induced change in the membrane structure using a fluorescent probe].
作者信息
Gorbenko G P, Diubko T S
出版信息
Ukr Biokhim Zh (1978). 1995 Jan-Feb;67(1):100-5.
PMID:8588245
Abstract
The effect of radiation on erythrocyte membrane structure has been investigated using fluorescent probe 4-(n-dimethyl aminostyryl)-1-methylpyridinium n-toluolsulfonate. The form of fluorescence spectra was analyzed and inhomogeneous broadening parameters of spectral components were estimated. It was shown that in erythrocyte membrane there were three types of DSM binding sites. The physico-chemical properties of DSM surrounding and probes distribution were found to change after irradiation.
摘要
利用荧光探针4-（N-二甲基氨基苯乙烯基）-1-甲基吡啶对甲苯磺酸盐研究了辐射对红细胞膜结构的影响。分析了荧光光谱的形式，并估算了光谱成分的非均匀展宽参数。结果表明，红细胞膜中存在三种类型的DSM结合位点。发现照射后DSM周围的物理化学性质和探针分布发生了变化。
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