Lehnert T, Otto G, Herfarth C
Department of Surgery, University of Heidelberg, Germany.
World J Surg. 1995 Mar-Apr;19(2):252-63. doi: 10.1007/BF00308635.
During the past decade considerable progress has been reported in the treatment of primary and secondary hepatic malignancies. Refined techniques in surgery, transplantation, radiotherapy, and chemotherapy apparently have made the delivery of treatment safer. At the same time improved understanding of tumor biology has been incorporated in treatment strategies. More recently specific and nonspecific, active and passive immunotherapies have excited wide interest, and information from the first randomized studies is now available. We review current treatment options for primary and secondary hepatic malignancies in an attempt to extract plausible treatment guidelines and to identify promising future directions.
在过去十年中，原发性和继发性肝脏恶性肿瘤的治疗已取得了相当大的进展。手术、移植、放疗和化疗等技术的改进显然使治疗的实施更加安全。与此同时，对肿瘤生物学的深入理解已被纳入治疗策略中。最近，特异性和非特异性、主动和被动免疫疗法引起了广泛关注，现在已有首批随机研究的相关信息。我们回顾了原发性和继发性肝脏恶性肿瘤目前的治疗选择，试图提炼出合理的治疗指南，并确定未来有前景的方向。
