基于对自身H-2抗原亲和力低的前体细胞的胸腺选择的细胞毒性T细胞双识别模型。 - Suppr

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A dual recognition model for cytotoxic T cells based on thymic selection of precursors with low affinity for Self H-2 antigens.

作者信息

Blanden R V, Ada G L

出版信息

Scand J Immunol. 1978 Mar;7(3):181-90. doi: 10.1111/j.1365-3083.1978.tb00442.x.

DOI:10.1111/j.1365-3083.1978.tb00442.x

PMID:77550

Abstract

摘要

相似文献

A dual recognition model for cytotoxic T cells based on thymic selection of precursors with low affinity for Self H-2 antigens.基于对自身H-2抗原亲和力低的前体细胞的胸腺选择的细胞毒性T细胞双识别模型。

Scand J Immunol. 1978 Mar;7(3):181-90. doi: 10.1111/j.1365-3083.1978.tb00442.x.

Thymus and lymphohemopoietic cells: their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control.胸腺与淋巴造血细胞：它们在T细胞成熟、T细胞H-2限制性特异性选择以及H-2连锁免疫反应基因控制中的作用。

Immunol Rev. 1978;42:224-70. doi: 10.1111/j.1600-065x.1978.tb00264.x.

Incomplete tolerance to MHC antigens in irradiation chimeras: implications for MHC restriction and self tolerance.辐射嵌合体中对MHC抗原的不完全耐受：对MHC限制和自身耐受的影响。

Immunol Rev. 1981;58:25-36. doi: 10.1111/j.1600-065x.1981.tb00348.x.

Induction of neonatal tolerance to H-2k in B6 mice does not allow the emergence of T cells specific for H-2k plus vaccinia virus.在B6小鼠中诱导对H-2k的新生期耐受性并不能使针对H-2k加痘苗病毒的T细胞出现。

J Exp Med. 1982 Sep 1;156(3):810-21. doi: 10.1084/jem.156.3.810.

In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells.在辐射嵌合体中，宿主H-2抗原决定供体细胞毒性细胞的免疫反应性。

Nature. 1977 Sep 29;269(5627):417-8. doi: 10.1038/269417a0.

Established murine cytolytic T-cell lines as tools for a somatic cell genetic analysis of T-cell functions.已建立的小鼠细胞溶解T细胞系作为T细胞功能体细胞遗传分析的工具。

Immunol Rev. 1980;51:125-56. doi: 10.1111/j.1600-065x.1980.tb00319.x.

Cytotoxic T cells learn specificity for self H-2 during differentiation in the thymus.细胞毒性T细胞在胸腺分化过程中学习对自身H-2的特异性。

Nature. 1978 Jan 19;271(5642):251-3. doi: 10.1038/271251a0.

T-cell hybrids as a source of antigen-specific factors.作为抗原特异性因子来源的T细胞杂交体。

Transplant Proc. 1980 Sep;12(3):427-31.

The biologic effects of allogeneic factor on T lymphocytes. II. The specificity of AEF-induced cytotoxic T lymphocytes.同种异体因子对T淋巴细胞的生物学效应。II. AEF诱导的细胞毒性T淋巴细胞的特异性。

J Immunol. 1980 Jan;124(1):114-20.

Inductive requirements for the generation of virus-specific T lymphocytes. III. Production of target cells lysable by poxvirus-specific and allospecific cytotoxic T lymphocytes with membrane fragments bearing viral and H-2 antigens.病毒特异性T淋巴细胞生成的诱导性需求。III. 用带有病毒和H-2抗原的膜片段产生可被痘病毒特异性和同种特异性细胞毒性T淋巴细胞裂解的靶细胞。

J Immunol. 1980 Apr;124(4):1997-2003.

引用本文的文献

Anti-self receptors. I. Direct detection of H-2L region-restricted receptors on murine thymocytes.抗自身受体。I. 小鼠胸腺细胞上H-2L区域限制性受体的直接检测。

J Exp Med. 1980 Mar 1;151(3):553-65. doi: 10.1084/jem.151.3.553.

Suppression of T cells specific for the nonthymic parental H-2 haplotype in thymus-grafted chimeras.胸腺移植嵌合体中对非胸腺亲本H-2单倍型特异的T细胞的抑制

J Exp Med. 1980 Jan 1;151(1):246-51. doi: 10.1084/jem.151.1.246.

T cell recognition of antigen in vivo: role of the H-2 complex.体内T细胞对抗原的识别：H-2复合体的作用。

Springer Semin Immunopathol. 1980 Aug;3(2):213-45. doi: 10.1007/BF02053976.

Frequencies of alloreactive cytotoxic T-lymphocyte precursors responding to H-2 antigens alone.仅对H-2抗原产生反应的同种异体反应性细胞毒性T淋巴细胞前体的频率。

Immunology. 1980 Jun;40(2):163-9.

Antigen recognition by H-2-restricted cytolytic T lymphocytes is not mediated by two independent receptors.H-2 限制性细胞溶解T淋巴细胞的抗原识别不是由两个独立的受体介导的。

J Exp Med. 1984 Jan 1;159(1):330-5. doi: 10.1084/jem.159.1.330.

The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity.T细胞上主要组织相容性复合体限制的抗原受体。IV. 一种抗独特型抗体可预测抗原及I特异性。

J Exp Med. 1983 Nov 1;158(5):1635-46. doi: 10.1084/jem.158.5.1635.

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.抗原诱导的、H-2限制的、产生白细胞介素-2的T细胞杂交瘤。缺乏独立的抗原和H-2识别。

J Exp Med. 1981 May 1;153(5):1198-214. doi: 10.1084/jem.153.5.1198.

Thymic selection of the T-cell repertoire.T细胞库的胸腺选择。

Immunol Res. 1988;7(4):318-28. doi: 10.1007/BF02935536.

Mammalian T-lymphocyte antigen receptor genes: genetic and nongenetic potential to generate variability.哺乳动物T淋巴细胞抗原受体基因：产生变异性的遗传和非遗传潜力。

Hum Genet. 1987 Apr;75(4):300-10. doi: 10.1007/BF00284099.

Role of prethymic cells in acquisition of self-tolerance.胸腺前体细胞在获得自身耐受性中的作用。

J Exp Med. 1979 Dec 1;150(6):1351-8. doi: 10.1084/jem.150.6.1351.

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