肌动蛋白和微管依赖性细胞器马达：两种运动系统之间的相互关系。

Actin- and microtubule-dependent organelle motors: interrelationships between the two motility systems.

作者信息

Langford G M

机构信息

Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA.

出版信息

Curr Opin Cell Biol. 1995 Feb;7(1):82-8. doi: 10.1016/0955-0674(95)80048-4.

DOI:10.1016/0955-0674(95)80048-4

PMID:7755993

Abstract

Membranous organelles move on both actin filaments and microtubules. Evidence for the presence of myosin and microtubule-based motors on the same organelle has raised the question of the interrelationship between the two motility systems. Functional studies of unconventional myosins are beginning to provide insights into this question and the important roles these motors play in membrane trafficking and organelle movement.

摘要

膜性细胞器在肌动蛋白丝和微管上移动。同一细胞器上存在肌球蛋白和基于微管的马达蛋白的证据，引发了这两种运动系统之间相互关系的问题。对非常规肌球蛋白的功能研究开始为这个问题以及这些马达蛋白在膜运输和细胞器移动中所起的重要作用提供见解。