Yamashita R A, May G S
Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030-3498, USA.
Curr Opin Cell Biol. 1998 Feb;10(1):74-9. doi: 10.1016/s0955-0674(98)80088-4.
This review discusses molecular motors that use the microfilament and microtubule cytoskeletal systems in filamentous fungi. There has been an explosion in our knowledge of kinesins over the past year, because of the integration of genetic and biochemical data. The recognition of possible interactions between septation genes and cytokinesis has also advanced our understanding of microfilament-based cytoskeletal systems. We review recent findings on microfilament motors, including conventional and unconventional myosins, and the microtubule motors of the kinesin family and cytoplasmic dynein. The roles that these molecules play in hyphal morphogenesis and organelle transport provide an insight into cytoskeletal-based transport systems.
本综述讨论了丝状真菌中利用微丝和微管细胞骨架系统的分子马达。由于遗传数据和生化数据的整合，过去一年我们对驱动蛋白的了解有了极大的增长。对隔膜形成基因与胞质分裂之间可能存在的相互作用的认识，也增进了我们对基于微丝的细胞骨架系统的理解。我们综述了微丝马达（包括传统和非传统肌球蛋白）以及驱动蛋白家族和胞质动力蛋白的微管马达的最新研究结果。这些分子在菌丝形态发生和细胞器运输中所起的作用，为基于细胞骨架的运输系统提供了深入了解。
