Kopniczky Z, Barzó P, Pávics L, Dóczi T, Bodosi M, Csernay L
Department of Neurosurgery, Albert Szent-Györgyi University, Szeged, Hungary.
Childs Nerv Syst. 1995 Feb;11(2):102-6. doi: 10.1007/BF00303814.
The authors present the policy they have worked out for hydrocephalus patients with special reference to the pressure measurement and test methods and to rCBF, SPECT and transcranial Doppler sonography (TDC) studies. For diagnosis, the protocol proposed by Gjerris and Borgesen was followed in 75 cases: besides other methods (CT, radionuclide cisternography, MRI) the intracranial pressure waves routinely recorded and analyzed by means of ventricular catheters for 24 h. The patients were roughly divided into groups in terms of diagnosis, baseline pressure, compliance, results of infusion tests and of surgery. In 13 patients the investigations were supplemented by rCBF SPECT and in 42 patients by TCD studies before and after CSF shunting or withdrawal to analyze the acute effects on cerebral circulation. Clinical follow-up shows that need for shunting was indicated fairly well by the common results of baseline ICP, compliance and infusion loading. The rCBF SPECT studies revealed a significant increase of the cerebral perfusion at the basal ganglia after shunting while, on the basis of CBF velocity changes three types of vasoregulatory response could be defined with TCD. In our hands, monitoring of the pressure and craniospinal capacity has proved to be a valuable aid in decisions on surgery; however, for a more precise (and beneficial) appreciation of whether surgery is indicated the vasoregulatory responses should also be taken into account in future.
作者介绍了他们为脑积水患者制定的政策,特别提及压力测量和测试方法以及局部脑血流量(rCBF)、单光子发射计算机断层扫描(SPECT)和经颅多普勒超声(TDC)研究。为进行诊断,75例患者遵循了Gjerris和Borgesen提出的方案:除其他方法(计算机断层扫描、放射性核素脑池造影、磁共振成像)外,还通过脑室导管常规记录和分析颅内压力波24小时。根据诊断、基线压力、顺应性、输液试验结果和手术结果,将患者大致分组。13例患者的研究通过rCBF SPECT进行补充,42例患者在脑脊液分流或引流前后通过经颅多普勒超声(TCD)研究进行补充,以分析对脑循环的急性影响。临床随访表明,基线颅内压、顺应性和输液负荷的共同结果能较好地提示分流的必要性。rCBF SPECT研究显示分流后基底节区脑灌注显著增加,而基于脑血流速度变化,经颅多普勒超声(TCD)可定义三种类型的血管调节反应。在我们的实践中,压力和颅脊髓容量监测已被证明是手术决策中的一项有价值的辅助手段;然而,为了更精确(且有益)地判断是否需要手术,未来还应考虑血管调节反应。