Enk B, Lund B, Schmidt A, Deckert T
Acta Endocrinol (Copenh). 1976 Jun;82(2):306-11.
Intravenous injection of the gastro-intestinal hormone secretin elicits an increase in the insulin concentration in the cubital vein. In 10 normal weight non-diabetics and 10 obese non-diabetics the latter group gave a hypernormal insulin response. By the simultaneous determination of the insulin concentration in the cubital and portal veins and also by an investigation of 2 pancreatectomized patients, it was demonstrated that an increase in the cubital insulin concentration following intravenous injection of secretin was due to an altered secretion from the pancreas and not to an altered elimination of insulin.
静脉注射胃肠激素促胰液素会引起肘静脉中胰岛素浓度升高。在10名正常体重的非糖尿病患者和10名肥胖非糖尿病患者中，后一组呈现出超正常的胰岛素反应。通过同时测定肘静脉和门静脉中的胰岛素浓度，以及对2名胰腺切除患者的研究表明，静脉注射促胰液素后肘静脉胰岛素浓度升高是由于胰腺分泌改变，而非胰岛素清除改变所致。
