Hanus M, Matouskova M, Smolova H
UroCentrum, Prague, Czech Republic.
Int Urol Nephrol. 1994;26(6):655-60. doi: 10.1007/BF02767720.
TNM classification allows only a partial estimation of future tumour behaviour after surgery. More knowledge on malignant potential is needed. Spreading of viable tumour cells during transurethral resection (TUR) and their possible subsequent implantation in the bladder mucosa should be an important factor influencing duration of the tumour-free interval (TFI). A total of 1384 fresh urine samples sequentially taken after surgery from 356 patients were examined in a cytological laboratory. Data analysis confirmed significant differences in TFI between the groups with negative, suspicious and positive cytology. The higher the cytological abnormalities the shorter was TFI, regardless of which histopathological tumour grade has been verified.
TNM 分类仅能对手术后肿瘤的未来行为进行部分评估。还需要更多关于恶性潜能的知识。经尿道切除术(TUR)期间存活肿瘤细胞的播散及其随后在膀胱黏膜中的可能植入应是影响无瘤间期(TFI)持续时间的一个重要因素。一家细胞学实验室对 356 例患者术后依次采集的总共 1384 份新鲜尿液样本进行了检查。数据分析证实,细胞学检查结果为阴性、可疑和阳性的组之间在 TFI 方面存在显著差异。无论已证实的组织病理学肿瘤分级如何,细胞学异常程度越高,TFI 越短。