Marquez G A, Klausner J S, Osborne C A
Department of Small Animal Clinical Science, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA.
J Am Vet Med Assoc. 1995 Mar 15;206(6):817-9.
A 9-year-old castrated male domestic shorthair cat with dysuria, anorexia, vomiting, and lethargy was admitted to the veterinary teaching hospital. A large, firm mass was palpable in the ventral cervical region. Hypercalcemia, azotemia, and nonregenerative anemia were evident on serum biochemical analysis and CBC, and multiple uroliths were detected by abdominal radiography. At necropsy, light microscopy of the ventral cervical mass revealed a parathyroid adenocarcinoma. Light microscopy of sections of the kidneys revealed multifocal, chronic, lymphocytic/plasmacytic, tubulointerstitial nephritis, as well as moderate multifocal acute tubular necrosis. On quantitative analysis, the uroliths were composed of calcium oxalate. Determination of serum calcium concentration is indicated in cats with calcium oxalate urolithiasis to aid in detection of primary hyperparathyroidism.
一只9岁去势家养短毛公猫，出现排尿困难、厌食、呕吐和嗜睡症状，被收治于兽医教学医院。在颈腹侧区域可触及一个大而硬的肿块。血清生化分析和血常规检查显示高钙血症、氮质血症和非再生性贫血，腹部X光检查发现多个尿路结石。尸检时，颈腹侧肿块的光镜检查显示为甲状旁腺癌。肾脏切片的光镜检查显示多灶性、慢性、淋巴细胞/浆细胞性肾小管间质性肾炎，以及中度多灶性急性肾小管坏死。定量分析显示，尿路结石由草酸钙组成。对于患有草酸钙尿路结石的猫，建议测定血清钙浓度，以帮助检测原发性甲状旁腺功能亢进。
