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[通过醋酸纤维素电泳法对生前和死后人体血液蛋白质谱的时间依赖性变化(作者译)]

[Time-dependant changes in the protein spectrum of blood from living and dead persons by means of electrophoresis in cellulose acetate (author's transl)].

作者信息

Mittmeyer H J, Schwend J

出版信息

Z Rechtsmed. 1978 Mar 28;81(1):19-24. doi: 10.1007/BF00200595.

Abstract

Protein electrophoresis on cellulose acetate shows that with increasing hemolysis of ante- and postmortem blood an extragradient in the alpha2-globulin field is created, which influences the relative ratio in the electropherogram. Strong hemolysis causes a fusion of the alpha2- and beta-globulin chains. In order to make a diagnostic interpretation of postmortem blood by means of electrophoresis, it is therefore essential to take into account the degree of hemolysis. Changes in the electrophoretic pattern due to hemolysis correlate best with the period of storage. With regard to timing for forensic purposes, the value is, however, limited.

摘要

醋酸纤维素薄膜蛋白电泳显示,生前和死后血液溶血程度增加时,α2球蛋白区域会出现额外梯度,这会影响电泳图谱中的相对比例。强烈溶血会导致α2球蛋白链和β球蛋白链融合。因此,为了通过电泳对死后血液进行诊断性解读,必须考虑溶血程度。溶血引起的电泳图谱变化与储存时间最相关。然而,就法医鉴定的时间而言,其价值有限。

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