Lin F R, Yao E G
Department of Hematology, Second Affiliated Hospital, Hebei Medical College, Shijiazhuang.
J Tongji Med Univ. 1994;14(4):227-9. doi: 10.1007/BF02897674.
We investigated the responses of patients with malignant histiocytosis (MH) to the treatment of epotoside-based regimen. Of 11 evaluable cases, 9 (81.8%) achieved complete remission and 1 partial remission. 7 complete remission cases (77.7%) received only one therapeutic course. The side effects were mild and well-tolerated. We conclude that etoposide-containing regimen is highly effective and can be used as first-line treatment for MH and is worthy of further study.
我们研究了恶性组织细胞增多症（MH）患者对依托泊苷方案治疗的反应。在11例可评估病例中，9例（81.8%）达到完全缓解，1例部分缓解。7例完全缓解病例（77.7%）仅接受了一个疗程的治疗。副作用轻微且耐受性良好。我们得出结论，含依托泊苷的方案疗效显著，可作为MH的一线治疗方法，值得进一步研究。
