Williams E S, Mills K, Kwiatkowski D R, Thorne E T, Boerger-Fields A
Department of Veterinary Sciences, University of Wyoming, Laramie 82070.
J Wildl Dis. 1994 Oct;30(4):581-5. doi: 10.7589/0090-3558-30.4.581.
Diagnosis of sylvatic plague in a captive black-footed ferret (Mustela nigripes) was based on gross and microscopic lesions, fluorescent antibody tests, culture of Yersinia pestis, and immunohistochemistry. Gross lesions consisted of acute hemorrhage and necrosis associated with cervical and mesenteric lymph nodes, subcutaneous hemorrhages, and pulmonary edema. Acute edema, hemorrhage, and necrosis with numerous bacteria in blood vessels and sinusoids characterized microscopic lesions. Occurrence of fatal plague in a black-footed ferret potentially has significant implications for recovery of this endangered species due to the widespread distribution of plague in prairie dog colonies throughout historic black-footed ferret range.
圈养黑足雪貂（鼬属黑足鼬）的野生型鼠疫诊断基于大体和微观病变、荧光抗体检测、鼠疫耶尔森菌培养及免疫组织化学。大体病变包括与颈部和肠系膜淋巴结相关的急性出血和坏死、皮下出血及肺水肿。微观病变特征为急性水肿、出血和坏死，血管和血窦中有大量细菌。由于鼠疫在历史上黑足雪貂分布范围内的草原犬鼠群落中广泛传播，黑足雪貂发生致命鼠疫可能对这一濒危物种的恢复产生重大影响。
