Feigin V L, Wiebers D O, Whisnant J P, O'Fallon W M
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Stroke. 1995 Jun;26(6):924-9. doi: 10.1161/01.str.26.6.924.
The present study was conducted to investigate the incidence of stroke and 30-day case-fatality rates for stroke in a defined Russian population.
This is a population-based study that was established in 1982. All residents of an administratively defined and typical district of Novosibirsk (approximately 150,000 subjects) who had an incident (first-ever) stroke from January 1, 1982, through December 31, 1992, were registered.
During an 11-year study period, 3406 incident stroke patients were registered, for an overall crude average annual incidence rate of 202/100,000 population. The rates were higher with increasing age and were significantly higher for men than for women. The age- and sex-adjusted annual incidence rate of stroke declined from 271/100,000 in 1982 to 232/100,000 in 1992. Slowing of the decline in stroke incidence was observed after 1988, and stroke incidence increased slightly in 1992. No significant differences in 30-day stroke case-fatality rates were noted from 1982 through 1992, but a slight trend toward decreasing rates was observed after 1988. There was no major change in patient age at stroke onset.
Stroke incidence rates in Novosibirsk are among the highest in the world. We observed a decline in stroke incidence but little change in 30-day case-fatality rates in Novosibirsk from 1982 through 1992.
本研究旨在调查俄罗斯特定人群中中风的发病率及中风30天病死率。
这是一项基于人群的研究，于1982年开展。登记了新西伯利亚一个行政划定的典型区域内（约15万受试者）从1982年1月1日至1992年12月31日发生首次中风的所有居民。
在11年的研究期间，登记了3406例首次中风患者，总体粗年均发病率为202/10万人口。发病率随年龄增长而升高，男性显著高于女性。年龄和性别调整后的中风年发病率从1982年的271/10万降至1992年的232/10万。1988年后中风发病率下降速度放缓，1992年略有上升。1982年至1992年期间，30天中风病死率无显著差异，但1988年后有轻微下降趋势。中风发病时患者年龄无重大变化。
新西伯利亚的中风发病率位居世界最高之列。我们观察到1982年至1992年期间新西伯利亚中风发病率下降，但30天病死率变化不大。
