Kolominsky-Rabas P L, Sarti C, Heuschmann P U, Graf C, Siemonsen S, Neundoerfer B, Katalinic A, Lang E, Gassmann K G, von Stockert T R
Department of Neurology, Friedrich-Alexander Universitaet Erlangen-Nuremberg, Erlangen, Bavaria, Germany.
Stroke. 1998 Dec;29(12):2501-6. doi: 10.1161/01.str.29.12.2501.
In Germany, basic data on stroke morbidity are lacking. If a population-based register in former East Germany is excluded, only routine mortality statistics have thus far provided information on epidemiology of stroke. Therefore, a population-based register of stroke was set up in Southern Germany to determine incidence and case fatality in a defined German population.
The Erlangen Stroke Project (ESPro) is a prospective community-based study among the 101 450 residents of the city of Erlangen, Bavaria, Germany. Standard definitions and overlapping case-finding methods were used to identify all cases of first-ever stroke in all age-groups, occurring in the 2 years of registration (April 1, 1994, to March 31, 1996). All identified cases of first-ever strokes were followed up at 3 and 12 months from onset.
During 2 years of registration, 354 first-ever-in-a-lifetime strokes (FELS) were registered. The diagnosis and stroke type were confirmed by CT scan in 95% of cases. Fifty-one percent of all FELS occurred in the age group >/=75 years of age. The crude annual incidence rate was 1.74 per 1000 (1.47 for men and 2.01 for women). After age-adjustment to the European population, the incidence rate was 1.34 per 1000 (1.48 for men and 1. 25 for women). The annual crude incidence rate of cerebral infarction was 1.37/1000, intracerebral hemorrhage 0.24/1000, subarachnoid hemorrhage 0.06/1000, and unspecified stroke 0.08/1000. Overall case fatality at 28 days was 19.4%, at 3 months it was 28.5%, and at 1 year 37.3%.
The first prospective community-based stroke register including all age groups in Germany revealed incidence rates of stroke similar to those reported from other population-based studies in western industrialized countries, but lower than that observed in former East Germany.
在德国，缺乏中风发病率的基础数据。若排除前东德基于人群的登记数据，目前仅有常规死亡率统计提供有关中风流行病学的信息。因此，在德国南部建立了一个基于人群的中风登记系统，以确定特定德国人群中的发病率和病死率。
埃尔朗根中风项目（ESPro）是一项针对德国巴伐利亚州埃尔朗根市101450名居民的前瞻性社区研究。采用标准定义和重叠病例发现方法，识别在登记的2年期间（1994年4月1日至1996年3月31日）所有年龄组中首次发生中风的所有病例。所有确诊的首次中风病例在发病后3个月和12个月进行随访。
在2年的登记期间，登记了354例首次发生的终生中风（FELS）。95%的病例通过CT扫描确诊了诊断和中风类型。所有FELS的51%发生在年龄≥75岁的年龄组。粗年发病率为每1000人1.74例（男性为1.47例，女性为2.01例）。经年龄调整为欧洲人群后，发病率为每1000人1.34例（男性为1.48例，女性为1.25例）。脑梗死的年粗发病率为1.37/1000，脑出血为0.24/1000，蛛网膜下腔出血为0.06/1000，未明确的中风为0.08/1000。28天时的总体病死率为19.4%，3个月时为28.5%，1年时为37.3%。
德国首个包括所有年龄组的前瞻性社区中风登记系统显示，中风发病率与西方工业化国家其他基于人群的研究报告的发病率相似，但低于在前东德观察到的发病率。
