Sperl J
I. interní klinika, 1. LF UK, Praha.
Vnitr Lek. 1995 Mar;41(3):182-4.
The activity of the inflammatory process in chronic viral hepatitis is conditioned by active replication of the virus in hepatocytes. The objective of treatment of chronic viral hepatitis is to arrest the virus replication, or preferably complete elimination. In recent years the first place in the treatment of chronic hepatitis was occupied by interferons, in particular interferon alpha. The course of the disease can be favourably influenced by treatment with interferon alpha in the half of patients with chronic active hepatitis B and in approximately one quarter of patients with chronic active hepatitis C. Treatment of chronic viral hepatitis in the author's department has been provided during the last three years and the achieved results are consistent with data in the literature.
慢性病毒性肝炎中炎症过程的活动取决于病毒在肝细胞中的活跃复制。慢性病毒性肝炎的治疗目标是阻止病毒复制，或者最好是彻底清除病毒。近年来，慢性肝炎治疗中占据首位的是干扰素，尤其是α干扰素。α干扰素治疗可使约一半的慢性乙型活动性肝炎患者和约四分之一的慢性丙型活动性肝炎患者的病情得到有利改善。作者所在科室在过去三年中对慢性病毒性肝炎进行了治疗，所取得的结果与文献中的数据一致。
