Watt J, Jones M L, Rose P, Pepper R
State Red Cell Reference Laboratory, NSW Red Cross BTS, Syndey, Australia.
Vox Sang. 1995;68(2):130-1. doi: 10.1111/j.1423-0410.1995.tb02565.x.
Anti-LU8, an antibody defining a high-frequency antigen in the Lutheran system, was identified in the serum of a gravida 4 para 0 pregnant women who had never been transfused. The antibody consisted of both an IgM and an IgG1 component and was nonreactive in the antibody-dependent cell-mediated cytotoxicity (ADCC) assay. The red cells of the mother and 3 siblings of the patient typed as LU:8,14 and were incompatible with the patient's serum. The baby was born at term with a negative direct antiglobulin test and typed as LU:8,14. There was no clinical evidence of haemolytic disease of the newborn.
抗-LU8是一种鉴定路德系统中高频抗原的抗体，在一名从未接受过输血的孕4产0孕妇血清中被发现。该抗体由IgM和IgG1成分组成，在抗体依赖性细胞介导的细胞毒性（ADCC）试验中无反应性。患者母亲和3个兄弟姐妹的红细胞血型为LU:8,14，与患者血清不相容。婴儿足月出生，直接抗球蛋白试验阴性，血型为LU:8,14。没有新生儿溶血病的临床证据。
