Höcker P, Knapp W, Linkesch W, Geissler K, Peters C, Hinterberger W, Wagner A
Abteilung für Transfusionsmedizin, Universität Wien.
Wien Med Wochenschr. 1995;145(2-3):27-9.
The methods of collection and storage of peripheral blood stem cells are described, and the harvesting after conditioning with cytokines and/or myelosuppressive therapy is discussed. It could be demonstrated that the combination of cytostatics and cytokines gives the best yield and enables to collect a sufficient amount of peripheral bloodstem cells for a successful engraftment after myeloablative therapy with only few aphereses.
描述了外周血干细胞的采集和储存方法,并讨论了在使用细胞因子和/或骨髓抑制疗法预处理后的采集情况。可以证明,细胞抑制剂和细胞因子的联合使用能获得最佳产量,并且仅需少量单采术就能采集到足够数量的外周血干细胞,用于清髓性治疗后成功植入。