Höcker P, Knapp W, Linkesch W, Geissler K, Peters C, Hinterberger W, Wagner A
Abteilung für Transfusionsmedizin, Institut für Blutgruppenserologie und Transfusionsmedizin, AKH Wien.
Beitr Infusionsther. 1993;31:130-5.
The methods of collection and storage of peripheral blood stem cells are described and the harvesting after conditioning with cytokines and/or myelosuppressive therapy is discussed. It could be demonstrated that the combination of cytostatics and cytokines gives the best yield and enables to collect a sufficient amount of peripheral blood stem cells for a successful engraftment after myeloablative therapy with only few aphereses.
本文描述了外周血干细胞的采集和储存方法，并讨论了在使用细胞因子和/或骨髓抑制疗法预处理后的采集情况。结果表明，细胞抑制剂和细胞因子的联合使用能获得最佳产量，并且只需进行少量单采术，就能采集到足够数量的外周血干细胞，用于清髓性治疗后成功植入。
