[Nature and mechanism of plaque formation (vesiculocytosis)].

According to N. N. Klemparskaya the process of plaque formation in the peripheral blood was the result of erythrocyte hemolysis by autohemolysins released by immunocompetent mononuclears--lymphocytes and plasma cells. However, such interpretation was not confirmed in investigation of the mentioned process. Plaque staining, cinemicrography and other methods showed plaque formation to occur on account of drawing apart the erythrocytes, not their hemolysis, by the substances which was released from the cells as a result of destructive processes with vesicle formation (vesiculocytosis). No vital activity or division of these cells was observed in the blood preparations. Polynuclears -- chiefly neutrophils, not mononuclears, served as the plaque-forming cells.