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慢性精神分裂症患者停用吩噻嗪的对照试验。

A controlled trial of phenothiazine withdrawal in chronic schizophrenic patients.

作者信息

Andrews P, Hall J N, Snaith R P

出版信息

Br J Psychiatry. 1976 May;128:451-5. doi: 10.1192/bjp.128.5.451.

DOI:10.1192/bjp.128.5.451
PMID:776312
Abstract

Phenothiazine drugs were withdrawn from 17 chronic schizophrenic in-patients, with a control group of 14 patients remaining on active medication. The trial was conducted under double blind conditions over a period of 42 weeks with weekly assessment of the patients by ward nurses. Of the placebo group 35% relapsed, relapse being related to the level of previous active medication.

摘要

对17名慢性精神分裂症住院患者停用了吩噻嗪类药物,另有14名患者组成对照组继续服用有效药物。该试验在双盲条件下进行,为期42周,病房护士每周对患者进行评估。安慰剂组中有35%的患者复发,复发与之前有效药物的使用剂量有关。

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