Stephan K M, Dettmers C, Frackowiak R S
Medical Research Council Cyclotron Unit, Hammersmith Hospital, London, UK.
Arzneimittelforschung. 1995 Mar;45(3A):390-3.
The potential mechanisms underlying recovery and reorganisation of the motor cortex are described on the basis of functional imaging studies. These were performed in normal subjects and patients over the past years by the Hammersmith group. The mechanisms of motor learning are discussed and altered patterns of activation after suffering from stroke, amyotrophic lateral sclerosis and amputation are described. The potential role of ispilateral cortical representation in the primary motor cortex, as well as the role of opercular premotor cortex, insular cortex and inferior parietal cortex are discussed.
基于功能成像研究描述了运动皮层恢复和重组的潜在机制。这些研究是过去几年由哈默史密斯小组在正常受试者和患者中进行的。讨论了运动学习的机制,并描述了中风、肌萎缩侧索硬化症和截肢后激活模式的改变。讨论了初级运动皮层中同侧皮层代表的潜在作用,以及岛盖前运动皮层、岛叶皮层和顶下小叶皮层的作用。