重组疫苗研发：一种控制体外寄生虫的新方法。基于皮蝇素A的牛皮蝇病重组疫苗研发综述。
Recombinant vaccine development: a novel approach to ectoparasite control. A review of development of a recombinant vaccine for hypodermosis based on hypodermin A.
作者信息
Temeyer K B, Pruett J H, Kuhn I, Files J
机构信息
Knipling-Bushland U.S. Livestock Insects Research Laboratory, U.S. Department of Agriculture, Kerrville, TX 78028-9184.
出版信息
SAAS Bull Biochem Biotechnol. 1993;6:31-5.
PMID:7763704
Abstract
Cattle grubs (Hypoderma lineatum and H. bovis) are obligate parasites of cattle for most of their one year life cycle. Previously exposed animals become resistant to productive reinfestation, presumably as a result of immune system involvement, suggesting potential control by vaccination. Research progress towards development and utilization of a recombinant subunit vaccine for hypodermosis is described.
摘要
牛皮蝇（纹皮蝇和牛皮蝇）在其一年的生命周期中的大部分时间都是牛的专性寄生虫。先前接触过的动物对再次感染具有抵抗力，推测这是免疫系统参与的结果，这表明可以通过疫苗接种进行潜在控制。本文描述了用于牛皮蝇蛆病的重组亚单位疫苗的研发和利用方面的研究进展。
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