刺五加叶中的皂苷

Saponins from leaves of Acanthopanax sieboldianus.

作者信息

Sawada H, Miyakoshi M, Isoda S, Ida Y, Shoji J

机构信息

School of Pharmaceutical Sciences, Showa University, Tokyo, Japan.

出版信息

Phytochemistry. 1993 Nov;34(4):1117-21. doi: 10.1016/s0031-9422(00)90727-1.

DOI:10.1016/s0031-9422(00)90727-1

PMID:7764238

Abstract

Two new triterpenoid saponins named sieboldianoside A and B were isolated from the leaves of Acanthopanax sieboldianus together with five known triterpenoid saponins, kalopanax-saponins A and B, saponin A, CP3, sapindoside B, and a known flavonol glycoside, kaempferol 3-O-rutinoside. On the basis of chemical and spectral evidence, the structures of the new saponins (sieboldianoside A and B) were concluded to be alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)- beta-D-glucopyranosyl esters of hederagenin and oleanolic acid 3-O-beta-D- xylopyranosyl(1-->3)-alpha-L-rhamnopyranosyl(1-->2)-alpha-L-arabinopy ranosides, respectively.

摘要

从刺五加叶中分离出两种新的三萜皂苷，命名为西伯利苷A和B，同时还分离出五种已知的三萜皂苷，刺五加皂苷A和B、皂苷A、CP3、无患子皂苷B，以及一种已知的黄酮醇苷，山柰酚3 - O - 芸香糖苷。基于化学和光谱证据，得出新皂苷（西伯利苷A和B）的结构分别为常春藤皂苷元的α - L - 鼠李吡喃糖基(1→4)-β - D - 葡萄糖吡喃糖基(1→6)-β - D - 葡萄糖吡喃糖基酯和齐墩果酸3 - O - β - D - 木糖吡喃糖基(1→3)-α - L - 鼠李吡喃糖基(1→2)-α - L - 阿拉伯吡喃糖苷。