Fulton S P
PerSeptive Biosystems Inc, Cambridge.
Curr Opin Biotechnol. 1994 Feb;5(2):201-5. doi: 10.1016/s0958-1669(05)80037-0.
Over the past year, a number of advances have been made in the large-scale purification of macromolecules, particularly proteins. Although refinements to individual unit operations have occurred, especially in improving the speed of operation and performance of large-scale chromatographic media, a major research thrust has been the development of processes in which steps are combined or eliminated to improve operability and reduce cost.
在过去的一年里，大分子尤其是蛋白质的大规模纯化取得了许多进展。尽管对各个单元操作进行了改进，特别是在提高操作速度和大规模色谱介质性能方面，但一个主要的研究方向是开发将步骤合并或消除以提高可操作性并降低成本的工艺。
