Danzig L A, Coutis R D, Resnick D
Clin Orthop Relat Res. 1976 Jun(117):217-20.
Avascular necrosis of the femoral head occurred following cardiac transplantation in a 28-year-old man. After cardiac surgery the patient was treated with prednisone and experienced 2 "rejection" episodes. Hip pain began 5 months postoperatively. Roentgenograms revealed rapidly progressive avascular necrosis in both hips. The sequence of events leading to avascular necrosis of bone in this patient is identical to that following other organ transplantations and includes steroid-induced hyperlipemia, fatty infiltration of the liver, systemic fat emboli to subchondral vessels and avascular necrosis.
一名28岁男性在心脏移植后发生了股骨头缺血性坏死。心脏手术后，该患者接受了泼尼松治疗，并经历了2次“排斥”发作。术后5个月开始出现髋关节疼痛。X线片显示双侧髋关节迅速进展为缺血性坏死。导致该患者骨缺血性坏死的一系列事件与其他器官移植后发生的情况相同，包括类固醇诱导的高脂血症、肝脏脂肪浸润、系统性脂肪栓子进入软骨下血管以及缺血性坏死。
