Hickman J G, Tindall J P, McCollum D E
South Med J. 1979 Feb;72(2):121-3, 126. doi: 10.1097/00007611-197902000-00004.
Aseptic (avascular) necrosis of the femoral head associated with psoriasis is reported. The clinical histories of nine patients with avascular necrosis of the femoral head and one patient with bilateral humeral head osteonecrosis are summarized. Psoriasis was the only associated condition found in three of the patients. Only two patients had received systemic corticosteroids in significant amounts (greater than 1 gm of prednisone). Four patients had received methotrexate therapy for psoriasis. Other possible contributing factors including serum uric acid levels are discussed. Psoriasis should be added to the list of systemic diseases associated with aseptic (avascular) necrosis. Avascular necrosis of the femoral head should be considered in any patient with psoriasis and pain in the hip or thigh.
报告了与银屑病相关的股骨头无菌性（缺血性）坏死。总结了9例股骨头缺血性坏死患者和1例双侧肱骨头骨坏死患者的临床病史。银屑病是其中3例患者唯一发现的相关病症。只有2例患者接受过大量全身性皮质类固醇治疗（泼尼松超过1克）。4例患者因银屑病接受过甲氨蝶呤治疗。讨论了其他可能的促成因素，包括血清尿酸水平。银屑病应被列入与无菌性（缺血性）坏死相关的全身性疾病名单。任何患有银屑病且髋部或大腿疼痛的患者都应考虑股骨头缺血性坏死。
