Janssen D B, Schanstra J P
Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology, University of Groningen, The Netherlands.
Curr Opin Biotechnol. 1994 Jun;5(3):253-9. doi: 10.1016/0958-1669(94)90026-4.
Recently, significant new insight has been obtained into the structure and catalytic mechanism of enzymes that convert environmental pollutants. Recent advances in protein engineering make it possible to use this information for improving the catalytic performance of such enzymes to achieve increased stability and expanded substrate range.
最近,人们对转化环境污染物的酶的结构和催化机制有了重要的新认识。蛋白质工程的最新进展使利用这些信息来提高此类酶的催化性能以实现更高的稳定性和更广泛的底物范围成为可能。