Conway de Macario E, Macario A J
Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany.
Trends Biotechnol. 1994 Dec;12(12):512-8. doi: 10.1016/0167-7799(94)90059-0.
The Archaea are one of the three phylogenetic domains into which all organisms have been classified, and include extreme halophiles, extreme thermophiles and methanogens. Some of these organisms inhabit inhospitable environments on Earth, and thus have evolved stress responses to cope with the extremes of heat, pH and salinity that they encounter. Although the archaeal stress or heat-shock response bears some similarity to the heat-shock responses of other organisms, it possesses some unique features. A better understanding of this response would facilitate its exploitation in the biotechnological industries; for example, in engineering cells that exhibit an improved ability to withstand, or recover from, stress.
古菌是所有生物被分类进入的三个系统发育域之一，包括极端嗜盐菌、极端嗜热菌和产甲烷菌。其中一些生物栖息在地球上不适宜居住的环境中，因此进化出了应激反应来应对它们所遇到的极端高温、酸碱度和盐度。尽管古菌的应激或热休克反应与其他生物的热休克反应有一些相似之处，但它具有一些独特的特征。更好地理解这种反应将有助于在生物技术产业中对其加以利用；例如，用于构建具有更强抗应激能力或从应激中恢复能力的工程细胞。
