Sakuda S, Miki K, Kitaoka S, Reugjitchachawaly M, Yamada Y
Department of Biotechnology, Faculty of Engineering, Osaka University, Japan.
Biosci Biotechnol Biochem. 1995 Jan;59(1):133-4. doi: 10.1271/bbb.59.133.
Tautomycetin was isolated as a regulator of secondary metabolite production for Penicillium urticae. It induced the simultaneous production of a yellow compound, named patulodin, and of patulolides against P. urticae P3, which does not produce such metabolites under the usual conditions. Tautomycin, a phosphatase inhibitor, also caused the same phenomenon.
互隔交链孢酚被分离出来作为荨麻青霉次级代谢产物产生的调节剂。它诱导同时产生一种名为展青霉素的黄色化合物以及对荨麻青霉P3的展青霉素类化合物，而荨麻青霉P3在通常条件下不会产生这些代谢产物。磷酸酶抑制剂互隔交链孢酚也会导致同样的现象。
