Kanoe M, Abe K, Kai K, Blobel H
Department of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University, Japan.
Lett Appl Microbiol. 1995 Mar;20(3):145-7. doi: 10.1111/j.1472-765x.1995.tb00412.x.
A cell wall preparation of Fusobacterium necrophorum induced haemorrhagic necrosis in the skins of guinea pigs and rabbits. Effects in mice and rats were weak or absent. The toxic activity of the cell wall preparation was not reduced by heat treatment. A dermonecrotic toxin was isolated from the cell wall preparation with sodium dodecylsulphate and concentrated by precipitation with ethanol. A preparation of the bacterial cytoplasm from Fus. necrophorum induced mainly erythema.
坏死梭杆菌的细胞壁制剂可在豚鼠和兔子的皮肤上引起出血性坏死。在小鼠和大鼠身上的效果较弱或无效果。细胞壁制剂的毒性活性不会因热处理而降低。用十二烷基硫酸钠从细胞壁制剂中分离出一种皮肤坏死毒素，并用乙醇沉淀进行浓缩。坏死梭杆菌的细菌细胞质制剂主要引起红斑。
