Kanoe M, Yamanaka M, Inoue M
Department of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University, Japan.
Med Microbiol Immunol. 1989;178(2):99-104. doi: 10.1007/BF00203305.
Thrombi formation was demonstrated in mesenteric microcirculation of guinea pigs inoculated with Fusobacterium necrophorum and the bacterial hemagglutinin (HA). The thrombi were initially observed in venules and later, in arterioles. Immunofluorescence study revealed that the HA bound to the thrombi in the microcirculation. These results indicate that thrombosis is an early step in the pathogenesis of necrosis.
在接种坏死梭杆菌和细菌血凝素（HA）的豚鼠肠系膜微循环中证实有血栓形成。血栓最初在小静脉中观察到，随后在小动脉中出现。免疫荧光研究显示，HA与微循环中的血栓结合。这些结果表明，血栓形成是坏死发病机制的早期步骤。
