Bell T N
Crit Care Nurs Clin North Am. 1994 Dec;6(4):675-85.
When the critically ill patient's clinical course is complicated by diabetes insipidus, a significant threat to the equilibrium of the body's delicate water and electrolyte balance ensues. Patients with diabetes insipidus are at significant risk of dehydration, hypernatremia, alterations in level of consciousness, and hemodynamic instability from hypovolemia. This article presents the causes of, and pathophysiologic alterations in, central and nephrogenic diabetes insipidus. Clinical manifestations and therapeutic management of both conditions in the critical care population are described.
当危重症患者的临床病程并发尿崩症时，就会对人体脆弱的水和电解质平衡的稳定构成重大威胁。尿崩症患者面临着脱水、高钠血症、意识水平改变以及因血容量不足导致的血流动力学不稳定等重大风险。本文介绍了中枢性尿崩症和肾性尿崩症的病因及病理生理改变。还描述了这两种病症在重症监护人群中的临床表现及治疗管理。
