Lewis M A, Webb N J, Stellman-Ward G R, Bannister C M
Children's Hospital, Manchester, England.
Eur J Pediatr Surg. 1994 Dec;4 Suppl 1:29-31. doi: 10.1055/s-2008-1066150.
The case records of 72 patients attending a multidisciplinary spina bifida clinic were reviewed to discover the prevalence of renal parenchymal damage. 19.4% of the total population had such damage. More detailed analysis of the group according to age showed that the prevalence of parenchymal damage in the over ten year olds (27.3%), was twice that of the under five year olds (13.3%) but the same as the prevalence of "at risk" patients (26.6%) in this group. On the basis that most renal parenchymal damage occurs early we conclude that the current approach to investigation and treatment is reducing the incidence of renal parenchymal damage in this population. Further reduction would require the early identification of the high risk bladder before the onset of hydronephrosis.
对一家多学科脊柱裂诊所72名患者的病例记录进行了回顾,以了解肾实质损害的患病率。在全部患者中,19.4%有此类损害。根据年龄对该组进行更详细分析显示,10岁以上儿童的实质损害患病率(27.3%)是5岁以下儿童(13.3%)的两倍,但与该组中“有风险”患者的患病率(26.6%)相同。基于大多数肾实质损害发生在早期这一情况,我们得出结论,目前的检查和治疗方法正在降低该人群中肾实质损害的发生率。进一步降低需要在肾积水发生之前尽早识别出高风险膀胱。