Nam J
Biostatistics Branch, National Cancer Institute, Rockville, Maryland 20892, USA.
Biometrics. 1995 Mar;51(1):354-7.
Eguchi and Matsuura (1990, Biometrics 46, 415-426) noted that the generalized Stevens test statistic for the Hardy-Weinberg law for human leukocyte antigen (HLA) data yields an excessively large value when no double blanks are observed. In this paper, we investigated this aberrant case. The inflated value of the test statistic is caused mainly by a seriously biased Bernstein's estimator of the recessive. We propose the generalized Stevens test using bias-corrected Bernstein's estimators for HLA data with no observed double blanks. An example illustrates the correction of the test statistic.
江口和松浦(1990年,《生物统计学》46卷,415 - 426页)指出,针对人类白细胞抗原(HLA)数据的哈迪 - 温伯格定律的广义史蒂文斯检验统计量,在未观察到双空白时会产生过大的值。在本文中,我们研究了这种异常情况。检验统计量的膨胀值主要是由隐性基因的伯恩斯坦估计量严重偏差导致的。我们针对未观察到双空白的HLA数据,提出使用偏差校正后的伯恩斯坦估计量的广义史蒂文斯检验。一个例子说明了检验统计量的校正。