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腹腔镜下双侧迷走神经干切断术联合内镜球囊扩张术治疗十二指肠溃疡

Laparoscopic treatment of duodenal ulcer by bilateral truncal vagotomy and endoscopic balloon dilatation.

作者信息

Ozmen V, Müslümanoğlu M, Iğci A, Buğra D

机构信息

University of Istanbul, Istanbul Medical School, Department of General Surgery, Türkiye.

出版信息

J Laparoendosc Surg. 1995 Feb;5(1):21-6. doi: 10.1089/lps.1995.5.21.

Abstract

The low morbidity and early recovery associated with laparoscopic procedures have shown a new direction for many types of surgery. We performed a laparoscopic bilateral truncal vagotomy (BTV) with pyloric dilatation (PD) in 20 patients (11 men, 9 women, ranging in age from 32 to 56 years, with a mean age of 42 years). All patients had chronic duodenal ulcer diagnosed endoscopically, with a mean duration of symptoms of 2.6 years (range 2-8 years). The mean length of surgery was 55 min (range 45-90 min). The mean follow-up period was 16 months (range 3-25 months). In 1 patient, esophageal perforation occurred during the dissection of the left vagus nerve and was sutured laparoscopically. Acid secretion tests under basal conditions and pentagastrin stimulation preoperatively and 1 month postoperatively showed a decrease in basal acid output (BAO) of 76% and maximal acid output (MAO) of 84.2%. Endoscopy at the second and sixth postoperative month showed healing of the ulcer in 19 of 20 patients (95%). One patient had partial pyloric stenosis due to chronic duodenal ulcer before BTV and PD and developed complete pyloric stenosis after the surgery. Despite repeated pyloric balloon dilatation, he required an open drainage procedure (gastroduodenostomy, Jaboulay). Three patients (15%) had postoperative diarrhea and responded very well to medical treatment. The preliminary results showed that laparoscopic BTV with PD is a simple and effective procedure for the treatment of chronic duodenal ulcer.

摘要

腹腔镜手术相关的低发病率和早期恢复为多种手术类型指明了新方向。我们对20例患者(11例男性,9例女性,年龄32至56岁,平均年龄42岁)实施了腹腔镜双侧迷走神经干切断术(BTV)并加做幽门扩张术(PD)。所有患者经内镜诊断为慢性十二指肠溃疡,症状平均持续时间为2.6年(范围2至8年)。手术平均时长为55分钟(范围45至90分钟)。平均随访期为16个月(范围3至25个月)。1例患者在分离左迷走神经时发生食管穿孔,经腹腔镜缝合。术前及术后1个月的基础胃酸分泌试验和五肽胃泌素刺激试验显示基础胃酸排量(BAO)降低76%,最大胃酸排量(MAO)降低84.2%。术后第2个月和第6个月的内镜检查显示,20例患者中有19例(95%)溃疡愈合。1例患者在BTV和PD术前因慢性十二指肠溃疡存在部分幽门狭窄,术后发展为完全性幽门狭窄。尽管反复进行幽门球囊扩张,他仍需要进行开放性引流手术(胃十二指肠吻合术,贾布莱术)。3例患者(15%)术后出现腹泻,经药物治疗效果良好。初步结果表明,腹腔镜BTV加PD是治疗慢性十二指肠溃疡的一种简单有效的方法。

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